K Hasegawa Selected Research

Phenylephrine (Neo-Synephrine)

5/2000	Phosphorylation of GATA-4 is involved in alpha 1-adrenergic agonist-responsive transcription of the endothelin-1 gene in cardiac myocytes.
1/2000	A nuclear complex containing PPARalpha/RXRalpha is markedly downregulated in the hypertrophied rat left ventricular myocardium with normal systolic function.

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K Hasegawa Research Topics

Disease

21	Neoplasms (Cancer) 12/2016 - 01/2000
9	Infections 01/2018 - 11/2001
6	Hepatocellular Carcinoma (Hepatoma) 01/2019 - 05/2000
6	Carcinoma (Carcinomatosis) 01/2016 - 01/2000
5	Ulcerative Colitis 09/2014 - 12/2000
5	Heart Failure 12/2001 - 05/2000
4	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2000
4	Obesity 01/2019 - 03/2001
4	Ovarian Neoplasms (Ovarian Cancer) 04/2017 - 04/2000
4	Glucose Intolerance 07/2013 - 04/2003
3	Carcinogenesis 12/2016 - 08/2001
3	Fibrosis (Cirrhosis) 12/2016 - 12/2006
3	Leukemia 06/2014 - 11/2001
3	Parkinson Disease (Parkinson's Disease) 10/2012 - 10/2000
3	Adenocarcinoma 02/2012 - 04/2001
3	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2011 - 03/2001
3	Rhinitis 12/2007 - 12/2004
3	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2005 - 11/2001
3	Stomach Neoplasms (Stomach Cancer) 10/2001 - 04/2000
3	Cardiomegaly (Heart Hypertrophy) 09/2000 - 01/2000
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 04/2004
2	Bronchiolitis 01/2018 - 11/2017
2	Liver Neoplasms (Liver Cancer) 04/2014 - 04/2012
2	Disease Progression 01/2013 - 09/2000
2	Hypertension (High Blood Pressure) 04/2008 - 09/2000
2	Proteinuria 04/2008 - 09/2000
2	Asthma (Bronchial Asthma) 07/2006 - 04/2002
2	Essential Hypertension 10/2005 - 10/2001
2	Contact Dermatitis (Eczema, Contact) 01/2005 - 12/2004
2	Dermatitis 01/2005 - 12/2004
2	Eczema 01/2005 - 12/2004
2	Inflammation (Inflammations) 01/2005 - 12/2004
2	Urticaria (Hives) 01/2005 - 12/2004
2	Necrosis 02/2004 - 05/2003
2	Glomerulonephritis 01/2003 - 11/2001
2	Amyloidosis 07/2001 - 03/2001
2	Myocardial Ischemia (Ischemic Heart Diseases) 03/2001 - 01/2000
2	Cholangitis 07/2000 - 05/2000
2	Stable Angina 06/2000 - 01/2000
1	Lymphatic Metastasis 01/2021
1	Portal Hypertension 01/2019
1	Cognitive Dysfunction 01/2019

Drug/Important Bio-Agent (IBA)

10	CytokinesIBA 01/2005 - 10/2000
6	InterferonsIBA 01/2016 - 10/2000
6	Messenger RNA (mRNA)IBA 07/2013 - 01/2000
5	Proteins (Proteins, Gene)FDA Link 12/2016 - 04/2000
4	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 12/2007 - 05/2003
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2005 - 01/2003
4	Monoclonal AntibodiesIBA 02/2004 - 04/2000
3	InterleukinsIBA 01/2016 - 10/2000
3	SteroidsIBA 01/2013 - 01/2005
3	Amyloid (Amyloid Fibrils)IBA 01/2012 - 03/2001
3	Pharmaceutical PreparationsIBA 01/2011 - 02/2001
3	AntibodiesIBA 02/2007 - 04/2000
3	CollagenIBA 12/2006 - 01/2000
2	Biomarkers (Surrogate Marker)IBA 01/2019 - 01/2001
2	Indicators and Reagents (Reagents)IBA 12/2016 - 09/2000
2	PlatinumIBA 01/2016 - 01/2007
2	LigandsIBA 06/2014 - 05/2000
2	Indocyanine Green (Cardio-Green)FDA LinkGeneric 04/2014 - 12/2011
2	LipidsIBA 07/2013 - 04/2004
2	LeptinIBA 07/2013 - 03/2001
2	Levodopa (L Dopa)FDA LinkGeneric 10/2012 - 10/2000
2	rho-Associated KinasesIBA 08/2012 - 04/2008
2	AlbuminsIBA 03/2012 - 09/2000
2	OvalbuminIBA 12/2007 - 04/2002
2	CPG-oligonucleotideIBA 02/2006 - 01/2003
2	OligodeoxyribonucleotidesIBA 02/2006 - 01/2003
2	Doxazosin (Cardura)FDA LinkGeneric 10/2005 - 10/2001
2	Olopatadine Hydrochloride (Patanol)FDA Link 01/2005 - 12/2004
2	OxazoloneIBA 01/2005 - 12/2004
2	Non-Sedating Histamine H1 Antagonists (Histamine H1 Antagonists, Non Sedating)IBA 01/2005 - 12/2004
2	Lymphocyte Function-Associated Antigen-1 (LFA-1)IBA 02/2004 - 05/2003
2	Interleukin-6 (Interleukin 6)IBA 05/2003 - 01/2003
2	Immunoglobulin G (IgG)IBA 01/2003 - 11/2001
2	Interferon-gamma (Interferon, gamma)IBA 01/2003 - 04/2002
2	Oxidants (Oxidizing Agents)IBA 12/2001 - 03/2001
2	p38 Mitogen-Activated Protein KinasesIBA 12/2001 - 03/2001
2	Fluorouracil (Carac)FDA LinkGeneric 09/2001 - 04/2000
2	Endothelin-1 (Endothelin 1)IBA 09/2001 - 05/2000
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 08/2001 - 05/2001
2	Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric 04/2001 - 01/2001
2	Human beta Subunit Chorionic GonadotropinIBA 04/2001 - 03/2000
2	doxifluridineIBA 03/2001 - 03/2001
2	Tumor Biomarkers (Tumor Markers)IBA 01/2001 - 07/2000
2	EnzymesIBA 01/2001 - 01/2000
2	Fas Ligand Protein (Fas Ligand)IBA 12/2000 - 05/2000
2	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 05/2000 - 01/2000

Therapy/Procedure

6	Therapeutics 04/2017 - 03/2001
5	Drug Therapy (Chemotherapy) 01/2021 - 05/2000
5	Liver Transplantation 09/2014 - 09/2001
2	Hepatectomy 01/2019 - 09/2000
2	Injections 01/2016 - 09/2000
2	Renal Dialysis (Hemodialysis) 11/2001 - 07/2001
2	Conservative Treatment 10/2001 - 05/2000
2	Radiotherapy 03/2001 - 03/2001
2	Immunotherapy 03/2001 - 03/2001
2	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 06/2000 - 01/2000
1	Adjuvant Chemotherapy 10/2019
1	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2019